Chapter 6: Molecular Basis of Inheritance
NCERT Solutions for CBSE Class 10 Biology — 30 solved questions with detailed explanations.
Solved Questions
Q1. DNA replication is:
- Conservative
- Semi-conservative
- Dispersive
- Random
Difficulty: Easy · Topic: DNA Replication
Solution
DNA replication is semi-conservative: each new DNA molecule has one old strand and one new strand (Meselson-Stahl experiment).
Q2. The central dogma of molecular biology is:
- DNA → RNA → Protein
- RNA → DNA → Protein
- Protein → RNA → DNA
- DNA → Protein → RNA
Difficulty: Easy · Topic: Central Dogma
Solution
Central dogma: DNA → (transcription) → RNA → (translation) → Protein.
Q3. The start codon is:
Difficulty: Easy · Topic: Genetic Code
Solution
AUG is the universal start codon. It codes for methionine (in eukaryotes) or f-Met (in prokaryotes).
Q4. RNA polymerase does not need:
- template
- nucleotides
- primer
- energy
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Q5. Restriction enzymes cut DNA at:
- any sequence
- centromeres
- palindromic sequences
- telomeres
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Solution
palindromic sequences.
Q6. Transformation was demonstrated by:
- Hershey and Chase
- Meselson and Stahl
- Watson and Crick
- Griffith (1928)
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Q7. DNA is the genetic material was proved by:
- Griffith
- Mendel
- Hershey and Chase
- Morgan
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Solution
Hershey and Chase.
Q8. Chargaff's rule states:
- A=T and G=C
- A=C and G=T
- A=G and T=C
- A+G=T+C
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Q9. Telomerase adds repetitive sequences to:
- telomeres
- origins
- promoters
- centromeres
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Q10. Griffith demonstrated:
- conjugation
- translation
- transduction
- transformation in bacteria
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Solution
transformation in bacteria.
Q11. Hershey-Chase used:
- neither
- only S
- T2 phage with ³²P and ³⁵S
- only P
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Solution
T2 phage with ³²P and ³⁵S.
Q12. Chargaff's rule: A=T, G=C applies to:
- double-stranded DNA
- protein
- single-stranded DNA
- RNA
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Solution
double-stranded DNA.
Q13. Telomerase maintains:
- telomere length
- origin firing
- promoter activity
- centromere function
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Q14. Operon concept given by:
- Morgan
- Mendel
- Watson and Crick
- Jacob and Monod
Difficulty: Easy · Topic: Molecular Basis of Inheritance
Q15. Okazaki fragments are formed during:
- transcription
- leading strand synthesis
- lagging strand synthesis
- translation
Difficulty: Easy-Medium · Topic: Molecular Basis of Inheritance
Solution
lagging strand synthesis.
Q16. Promoter in prokaryotes is recognized by:
- tRNA
- rho factor
- ribosome
- sigma factor of RNA polymerase
Difficulty: Easy-Medium · Topic: Molecular Basis of Inheritance
Solution
sigma factor of RNA polymerase.
Q17. Introns are:
- coding sequences
- regulatory sequences
- promoter sequences
- non-coding sequences in eukaryotic genes
Difficulty: Easy-Medium · Topic: Molecular Basis of Inheritance
Solution
non-coding sequences in eukaryotic genes.
Q18. Exons are:
- repetitive sequences
- intergenic sequences
- non-coding sequences
- coding sequences
Difficulty: Easy-Medium · Topic: Molecular Basis of Inheritance
Solution
coding sequences.
Q19. Lac operon is an example of:
- constitutive expression
- repressible operon
- inducible operon
- none
Difficulty: Easy-Medium · Topic: Molecular Basis of Inheritance
Solution
inducible operon.
Q20. Human genome has approximately:
- 3.2 billion base pairs
- 100 million bp
- 10 billion bp
- 1 million bp
Difficulty: Easy-Medium · Topic: Molecular Basis of Inheritance
Solution
3.2 billion base pairs.
Q21. DNA polymerase adds nucleotides in:
- both directions
- 5'→3' direction
- random
- 3'→5'
Difficulty: Easy-Medium · Topic: Molecular Biology
Q22. RNA polymerase reads template in:
- random
- both
- 3'→5' direction
- 5'→3'
Difficulty: Easy-Medium · Topic: Molecular Biology
Q23. mRNA moves from:
- stays in cytoplasm
- nucleus to cytoplasm (ribosome)
- stays in nucleus
- cytoplasm to nucleus
Difficulty: Easy-Medium · Topic: Molecular Biology
Solution
nucleus to cytoplasm (ribosome).
Q24. tRNA carries:
- DNA to ribosome
- amino acids to ribosome
- nothing
- mRNA to nucleus
Difficulty: Easy-Medium · Topic: Molecular Biology
Solution
amino acids to ribosome.
Q25. rRNA is found in:
- ribosomes
- nucleus only
- mitochondria only
- Golgi
Difficulty: Easy-Medium · Topic: Molecular Biology
Q26. Stop codons are:
- none
- GCC, GCA, GCU
- AUG, AUA, AUC
- UAA, UAG, UGA
Difficulty: Easy-Medium · Topic: Molecular Biology
Q27. Wobble hypothesis explains:
- flexibility in 3rd codon position
- lipid synthesis
- protein folding
- DNA structure
Difficulty: Easy-Medium · Topic: Molecular Biology
Solution
flexibility in 3rd codon position.
Q28. Operon model was proposed for:
- E. coli lac operon
- plant genome
- human genome
- viral genome
Difficulty: Easy-Medium · Topic: Molecular Biology
Solution
E. coli lac operon.
Q29. Enhancers are:
- introns
- tRNA genes
- regulatory DNA sequences far from promoter
- coding sequences
Difficulty: Easy-Medium · Topic: Molecular Biology
Solution
regulatory DNA sequences far from promoter.
Q30. Silencers are:
- structural genes
- sequences that decrease transcription
- coding regions
- sequences that increase transcription
Difficulty: Easy-Medium · Topic: Molecular Biology
Solution
sequences that decrease transcription.
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